Idioms of lifetime in English

the chance, etc. of a lifetime

a wonderful opportunity, etc. that you are not likely to get again

When she was offered the job she knew it was the chance of a lifetime.

the trip/experience/opportunity of a lifetime

once in a lifetime

used to describe something special that is not likely to happen to you again

An opportunity like this comes once in a lifetime.

a once-in-a-lifetime experience

That sort of thing happens only once in a lifetime.